PERICOLI DALLA RISONANZA MAGNETICA
Viene
pubblicato un estensivo lavoro di raccolta di precedenti studi sugli effetti di
una macchina di indagine a risonanza magnetica su organismi cellulari sia umani
che di batteri.
Il risultato
di correlazione è positivo, per cui, pur valutando come questa tecnica sia
molto importante nella diagnostica ospedaliera in quanto non invasiva, gli
autori segnalano che debbono essere approfonditi gli studi per individuare
protocolli che determino condizioni di maggiore sicurezza.
( leggi QUI il post completo )
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MAGNETIC RESONANCE IMAGING (MRI):
A REVIEW OF GENETIC DAMAGE INVESTIGATIONS.
- 1 Department
of Radiology, University of Texas Health Science Center, San Antonio, United
States.
- 2 Department
of Biomedical Magnetic Resonance, Otto-von-Guericke-University Magdeburg,
Magdeburg, Germany. Electronic address: Mahsa.Fatahi@ovgu.de.
- 3 Department
of Biomedical Magnetic Resonance, Otto-von-Guericke-University Magdeburg,
Magdeburg, Germany; German Center for Neurodegenerative Disease (DZNE) Site,
Magdeburg, Germany; Leibniz Institute for Neurobiology, Magdeburg, Germany;
Center for Behavioral Brain Sciences, Magdeburg, Germany.
Abstract
Magnetic resonance imaging (MRI) is a powerful, non-invasive
diagnostic medical imaging technique widely used to acquire detailed
information about anatomy and function of different organs in the body, in both
health and disease. It utilizes electromagnetic fields of three different
frequency bands: static magnetic field (SMF), time-varying gradient magnetic
fields (GMF) in the kHz range and pulsed radiofrequency fields (RF) in the MHz
range. There have been some investigations examining the extent of genetic
damage following exposure of bacterial and human cells to all three frequency
bands of electromagnetic fields, as used during MRI: the rationale for these
studies is the well documented evidence of positive correlation between
significantly increased genetic damage and carcinogenesis. Overall, the
published data were not sufficiently informative and useful because of the
small sample size, inappropriate comparison of experimental groups, etc.
Besides, when an increased damage was observed in MRI-exposed cells, the fate
of such lesions was not further explored from multiple 'down-stream' events.
This review provides: (i) information on the basic principles used in MRI
technology, (ii) detailed experimental protocols, results and critical comments
on the genetic damage investigations thus far conducted using MRI equipment
and, (iii) a discussion on several gaps in knowledge in the current scientific
literature on MRI. Comprehensive, international, multi-centered collaborative
studies, using a common and widely used MRI exposure protocol (cardiac or brain
scan) incorporating several genetic/epigenetic damage end-points as well as
epidemiological investigations, in large number of individuals/patients are
warranted to reduce and perhaps, eliminate uncertainties raised in genetic
damage investigations in cells exposed in vitro and in vivo to MRI.
