Metanalisi
che include dieci studi sull'associazione
nel
lungo termine tra la cancerogenesi cerebrale e l'utilizzo del telefono cellulare.
Nelle
conclusioni si evidenzia come possa aumentare il rischio di un glioma negli
utenti della telefonia a lungo termine.
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Wireless Phone Use and Risk of Adult Glioma: Evidence from Meta-analysis
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ABSTRACT
Objective
Wireless phone use has been
increasing rapidly and is associated with the risk of glioma. Many studies have
been conducted on this association, but did not reach an agreement. The aim of
this meta-analysis was to determine the possible association between wireless
phone use and the risk of adult glioma.
Methods
Eligible studies were identified
by searching Pubmed and Embase till July 2017. The random- or fixed-effects
model was used to combine the results depending on the heterogeneity of the
analysis. Publication bias was evaluated using Begg’s funnel plot and Egger’s
regression asymmetry test. Subgroup analysis was performed to evaluate the
possible influence of these variables.
Results
A
total of 10 studies about the association of wireless phone use and the risk of
glioma were included in this meta-analysis. The combined odd’s ratio (OR) of
adult glioma associated with ever use of wireless phone was 1.03 (95%
CI=0.92–1.16) with high heterogeneity (I2=54.2%,
P=0.013). In the subgroup analyses, no significant association was found
amongtumor location in the temporal lobe and adult glioma risk, with ORs of
1.26 (95% CI=0.87–1.84), 0.93 (95%CI=0.69–1.24), 1.61 (95%CI=0.78–3.33),
respectively. Significant association was found in long-term users (≥10 years)
with OR 1.33 (95%CI =1.05–1.67) and risk of glioma.
Conclusions
Our analysis suggested that ever
use of wireless phone was not significantly associated with the risk of adult
glioma, but could increase the risk in long-term users.
FONTE : ScienceDirect
