Translate

mercoledì 22 aprile 2015

LYMPHOMAS IN E MU-PIM1 TRANSGENIC MICE EXPOSED TO PULSED 900 MHZ ELECTROMAGNETIC FIELDS.

Storico articolo del 1997 ( quasi 20 anni fa ) dove i cellulari non erano certamente così diffusi e potenti, di Reapacholi che stranamente abbandonò la ricerca indipendente per diventare un oppositore del Principio di Precauzione, determinando quel fronte negazionista  che imperversa ancora oggi, con questo studio dimostrò un incremento di 2,4 volte di linfomi per topi esposti alle frequenze di un GSM 900 MHz. ( lo studio venne poi replicato per 2 volte con successo da ricercatori indipendenti australiani )

-------o-------o-------o-------o-------o-------

Radiat Res.
 1997 May;147(5):631-40.

Author information

·  1Royal Adelaide Hospital, Australia.

Abstract

Whether radiofrequency (RF) fields are carcinogenic is controversial; epidemiological data have been inconclusive and animal tests limited. The aim of the present study was to determine whether long-term exposure to pulse-modulated RF fields similar to those used in digital mobile telecommunications would increase the incidence of lymphoma in E mu-Pim1 transgenic mice, which are moderately predisposed to develop lymphoma spontaneously. One hundred female E mu-Pim1 mice were sham-exposed and 101 were exposed for two 30-min periods per day for up to 18 months to plane-wave fields of 900 MHz with a pulse repetition frequency of 217 Hz and a pulse width of 0.6 ms. Incident power densities were 2.6-13 W/m2 and specific absorption rates were 0.008-4.2 W/kg, averaging 0.13-1.4 W/kg. Lymphoma risk was found to be significantly higher in the exposed mice than in the controls (OR = 2.4. P = 0.006, 95% CI = 1.3-4.5). Follicular lymphomas were the major contributor to the increased tumor incidence. Thus long-term intermittent exposure to RF fields can enhance the probability that mice carrying a lymphomagenic oncogene will develop lymphomas. We suggest that such genetically cancer-prone mice provide an experimental system for more detailed assessment of dose-response relationships for risk of cancer after RF-field exposure.