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lunedì 15 febbraio 2016

META-ANALYSIS OF EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELDS AND CANCER RISK: A POOLED ANALYSIS OF EPIDEMIOLOGIC STUDIES.

Mentre aspettiamo da due anni la definizione di un protocollo per l’indagine epidemiologica eccoci a presentare l’ennesima metanalisi ( ma quante altre ne servono ancora per incominciare a considerare il problema ?? )  che racchiude ben 42 studi sui possibili effetti delle esposizioni alle basse frequenze ( elettrodotti ) ed il rischio di sviluppare cancro. 
I ricercatori hanno trovato una correlazione statisticamente significativa ( alto rischio ) tra esposizioni e sviluppo di cancro soprattutto in  ambito residenziale  quindi soggetti residenti in abitazioni collocate nei pressi di elettrodotti ( ma chi l’avrebbe mai detto !!!!!! ). 

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Environ Int. 2015 Dec 15;88:36-43. doi: 10.1016/j.envint.2015.12.012. [Epub ahead of print]
Meta-analysis of extremely low frequency electromagnetic fields and cancer risk: a pooled analysis of epidemiologic studies.
Author

1High Voltage Research Institute, China Electric Power Research Institute, Wuhan, People's Republic of China.
2Department of Internal Medicine and the Institute of Hypertension, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China.
3Department of Internal Medicine and the Institute of Hypertension, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China. Electronic address: chenchen@tjh.tjmu.edu.cn.
Abstract
Studies have suggested that extremely low frequency electromagnetic fields (ELF-EMF) may affect physiological functions in animal models. However, epidemiologic studies investigating the association of ELF-EMF with the susceptibility to cancer yield contradictory results. In this comprehensive analysis, we conducted a search for case-control surveys regarding the associations of ELF-EMF and cancer susceptibility in electronic databases. A total of42 studies involving 13,259 cases and 100,882 controls were retrieved. Overall, increased susceptibility to cancer was identified in the ELF-EMF exposed population (OR=1.08, 95% CI: 1.01, 1.15, P=0.02). In the stratified analyses, increased risk was found in North America (OR=1.10; 95% CI: 1.02, 1.20, P=0.02), especially the United States (OR=1.10; 95% CI: 1.01, 1.20, P=0.03). However, studies from Europe contradict these results. Moreover, a higher risk was found to be statistically significantly associated with the residential exposed population (OR=1.18; 95% CI: 1.02, 1.37, P=0.03). Furthermore, an increased cancer risk was found in interview-based surveys (OR=1.16; 95% CI: 1.00, 1.35, P=0.04). In device measurement-based studies, a slight increased risk was found only in premenopausal breast cancer (OR=1.23; 95% CI: 1.01, 1.49, P=0.04). Our meta-analysis suggests that ELF-EMFs are associated with cancer risk, mainly in the United States and in residential exposed populations. Methodological challenges might explain the differences among studies.


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